Compare GLP-1 Medications

GLP-1 receptor agonists are medications that help control blood sugar and promote weight loss. Compare the key differences between Ozempic, Wegovy, Mounjaro, Zepbound, Saxenda, and Victoza to find the right option for your needs.

Comparison of GLP-1 medications for diabetes and weight management
MedicationActive IngredientFDA Approved ForDosingAvg. Weight LossRetail Price
OzempicSemaglutide
Type 2 Diabetes
Once weekly injection (0.25mg - 2mg)12-15% body weight$1000/mo
WegovySemaglutide
Weight ManagementObesity
Once weekly injection (0.25mg - 2.4mg)15-20% body weight$1350/mo
MounjaroTirzepatide
Type 2 Diabetes
Once weekly injection (2.5mg - 15mg)15-21% body weight$1100/mo
ZepboundTirzepatide
Weight ManagementObesity
Once weekly injection (2.5mg - 15mg)18-22% body weight$1200/mo
SaxendaLiraglutide
Weight ManagementObesity
Daily injection (3mg)5-10% body weight$1400/mo
VictozaLiraglutide
Type 2 Diabetes
Daily injection (0.6mg - 1.8mg)5-8% body weight$850/mo

Ozempic

$1000/mo
Active Ingredient: Semaglutide
FDA Approved For:
Type 2 Diabetes
Dosing: Once weekly injection (0.25mg - 2mg)
Avg. Weight Loss: 12-15% body weight
Common Side Effects: Nausea, Diarrhea, Constipation, Abdominal pain

Wegovy

$1350/mo
Active Ingredient: Semaglutide
FDA Approved For:
Weight ManagementObesity
Dosing: Once weekly injection (0.25mg - 2.4mg)
Avg. Weight Loss: 15-20% body weight
Common Side Effects: Nausea, Diarrhea, Vomiting, Constipation

Mounjaro

$1100/mo
Active Ingredient: Tirzepatide
FDA Approved For:
Type 2 Diabetes
Dosing: Once weekly injection (2.5mg - 15mg)
Avg. Weight Loss: 15-21% body weight
Common Side Effects: Nausea, Diarrhea, Decreased appetite, Vomiting

Zepbound

$1200/mo
Active Ingredient: Tirzepatide
FDA Approved For:
Weight ManagementObesity
Dosing: Once weekly injection (2.5mg - 15mg)
Avg. Weight Loss: 18-22% body weight
Common Side Effects: Nausea, Diarrhea, Constipation, Vomiting

Saxenda

$1400/mo
Active Ingredient: Liraglutide
FDA Approved For:
Weight ManagementObesity
Dosing: Daily injection (3mg)
Avg. Weight Loss: 5-10% body weight
Common Side Effects: Nausea, Diarrhea, Constipation, Headache

Victoza

$850/mo
Active Ingredient: Liraglutide
FDA Approved For:
Type 2 Diabetes
Dosing: Daily injection (0.6mg - 1.8mg)
Avg. Weight Loss: 5-8% body weight
Common Side Effects: Nausea, Diarrhea, Headache, Hypoglycemia

Semaglutide (Ozempic & Wegovy)

Ozempic is FDA-approved for Type 2 diabetes, while Wegovy is the same molecule approved for weight management. Wegovy uses higher doses (up to 2.4mg) and typically results in greater weight loss. Both are once-weekly injections.

Tirzepatide (Mounjaro & Zepbound)

Mounjaro is approved for Type 2 diabetes, while Zepbound is approved for weight management. Tirzepatide is a dual agonist (GLP-1 and GIP), which may lead to greater weight loss compared to semaglutide-based medications.

Liraglutide (Victoza & Saxenda)

Victoza is for Type 2 diabetes, Saxenda for weight management. These are older GLP-1 medications requiring daily injections. Weight loss tends to be more modest compared to semaglutide and tirzepatide options.

Insurance Coverage

Diabetes medications (Ozempic, Mounjaro, Victoza) typically have better insurance coverage than weight loss versions (Wegovy, Zepbound, Saxenda). Always check with your insurance provider for specific coverage details.

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